Pre-RC Protein MCM7 depletion promotes mitotic exit by Inhibiting CDK1 activity

Pre-RC Protein MCM7 depletion promotes mitotic exit by Inhibiting CDK1 activity

Abstract MCM7, a subunit of mini-chromosome maintenance proteins (MCM) complex, plays an important role in initiating DNA replication during the G1 phase and extending DNA strands during the S phase. Here, we demonstrated that MCM7 is not only sustained but maintains association with chromatin durin...

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Bibliographic Details
Main Authors: Dianpeng Zheng, Sichao Ye, Xiuyun Wang, Yongjun Zhang, Daoyu Yan, Xiangsheng Cai, Weihong Gao, Hongbo Shan, Yang Gao, Juanjuan Chen, Zhiming Hu, Hongwei Li, Jinlong Li
Format: Article
Language:English
Published: Nature Publishing Group 2017-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-03148-3

Internet

https://doi.org/10.1038/s41598-017-03148-3

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