Connexin43 Containing Gap Junction Channels Facilitate HIV Bystander Toxicity: Implications in NeuroHIV

Human immunodeficiency virus-1 (HIV-1) infection compromises the central nervous system (CNS) in a significant number of infected individuals, resulting in neurological dysfunction that ranges from minor cognitive deficits to frank dementia. While macrophages/microglia are the predominant CNS cells...

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Bibliographic Details
Main Authors: Shaily Malik, Martin Theis, Eliseo A. Eugenin
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-12-01
Series:Frontiers in Molecular Neuroscience
Subjects:
HIV
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00404/full