Bach1-induced suppression of angiogenesis is dependent on the BTB domain

The transcription factor Bach1 impairs angiogenesis after ischemic injury by suppressing Wnt/β-catenin signaling; however, the specific domains responsible for the anti-angiogenic effects of Bach1 remain unclear. This study determined the role of the BTB domain of Bach1 in ischemic angiogenesis. Bac...

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Bibliographic Details
Main Authors: Li Jiang, Mengping Jia, Xiangxiang Wei, Jieyu Guo, Shengyu Hao, Aihong Mei, Xiuling Zhi, Xinhong Wang, Qinhan Li, Jiayu Jin, Jianyi Zhang, Shanqun Li, Dan Meng
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419308321