Molecular determinants of Ebola virus virulence in mice.

Molecular determinants of Ebola virus virulence in mice.

Zaire ebolavirus (ZEBOV) causes severe hemorrhagic fever in humans and nonhuman primates, with fatality rates in humans of up to 90%. The molecular basis for the extreme virulence of ZEBOV remains elusive. While adult mice resist ZEBOV infection, the Mayinga strain of the virus has been adapted to c...

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Bibliographic Details
Main Authors: Hideki Ebihara, Ayato Takada, Darwyn Kobasa, Steven Jones, Gabriele Neumann, Steven Theriault, Mike Bray, Heinz Feldmann, Yoshihiro Kawaoka
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC1513261?pdf=render

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http://europepmc.org/articles/PMC1513261?pdf=render

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