Recombinant human complement component C2 produced in a human cell line restores the classical complement pathway activity <it>in-vitro: </it>an alternative treatment for C2 deficiency diseases

<p>Abstract</p> <p>Background</p> <p>Complement C2 deficiency is the most common genetically determined complete complement deficiency and is associated with a number of diseases. Most prominent are the associations with recurrent serious infections in young children an...

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Main Authors: Martini Paolo GV, Cook Lynette C, Alderucci Scott, Norton Angela W, Lundberg Dianna M, Fish Susan M, Langsetmo Knut, Jönsson Göran, Lood Christian, Gullstrand Birgitta, Zaleski Kate J, Savioli Nancy, Lottherand Jason, Bedard Charles, Gill John, Concino Michael F, Heartlein Michael W, Truedsson Lennart, Powell Jan L, Tzianabos Arthur O
Format: Article
Language:English
Published: BMC 2010-08-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/11/43