Investigation of Elemental Mass Spectrometry in Pharmacology for Peptide Quantitation at Femtomolar Levels.

In the search of new robust and environmental-friendly analytical methods able to answer quantitative issues in pharmacology, we explore liquid chromatography (LC) associated with elemental mass spectrometry (ICP-MS) to monitor peptides in such complex biological matrices. The novelty is to use mass...

Full description

Bibliographic Details
Main Authors: Emmanuelle Cordeau, Carine Arnaudguilhem, Brice Bouyssiere, Agnès Hagège, Jean Martinez, Gilles Subra, Sonia Cantel, Christine Enjalbal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4918930?pdf=render