Reduction in Hindquarter Vascular Resistance Supports 5-HT7 Receptor Mediated Hypotension

The 5-HT7 receptor is the primary mediator of both the acute (<hours) and chronic (day-week) decreases in mean arterial pressure (MAP) during low dose 5-HT infusion in rats. Previous data show the hypotensive response during chronic 5-HT infusion is due to a decrease total peripheral resistan...

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Bibliographic Details
Main Authors: Bridget M. Seitz, Stephanie W. Watts, Gregory D. Fink
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Physiology
Subjects:
rat
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.679809/full