Generation of Organized Porcine Testicular Organoids in Solubilized Hydrogels from Decellularized Extracellular Matrix

Generation of Organized Porcine Testicular Organoids in Solubilized Hydrogels from Decellularized Extracellular Matrix

Cryopreservation of immature testicular tissue (ITT) prior to chemo/radiotherapy is now ethically accepted and is currently the only way to preserve fertility of prepubertal boys about to undergo cancer therapies. So far, three-dimensional culture of testicular cells isolated from prepubertal human...

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Bibliographic Details
Main Authors: Maxime Vermeulen, Federico Del Vento, Marc Kanbar, Sébastien Pyr dit Ruys, Didier Vertommen, Jonathan Poels, Christine Wyns
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:International Journal of Molecular Sciences
Subjects:
decellularization
extracellular matrix
immature testicular tissue
three-dimensional culture
testicular cells
organoids
fertility preservation
artificial testis
spermatogonial stem cells
Online Access:https://www.mdpi.com/1422-0067/20/21/5476

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https://www.mdpi.com/1422-0067/20/21/5476

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