Genome-wide association analysis in dogs implicates 99 loci as risk variants for anterior cruciate ligament rupture.

Anterior cruciate ligament (ACL) rupture is a common condition that can be devastating and life changing, particularly in young adults. A non-contact mechanism is typical. Second ACL ruptures through rupture of the contralateral ACL or rupture of a graft repair is also common. Risk of rupture is inc...

Full description

Bibliographic Details
Main Authors: Lauren A Baker, Brian Kirkpatrick, Guilherme J M Rosa, Daniel Gianola, Bruno Valente, Julia P Sumner, Wendy Baltzer, Zhengling Hao, Emily E Binversie, Nicola Volstad, Alexander Piazza, Susannah J Sample, Peter Muir
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5381864?pdf=render