Hedgehog Signaling Links Chronic Inflammation to Gastric Cancer Precursor LesionsSummary

Since its initial discovery in Drosophila, Hedgehog (HH) signaling has long been associated with foregut development. The mammalian genome expresses 3 HH ligands, with sonic hedgehog (SHH) levels highest in the mucosa of the embryonic foregut. More recently, interest in the pathway has shifted to im...

Full description

Bibliographic Details
Main Authors: Juanita L. Merchant, Lin Ding
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Cellular and Molecular Gastroenterology and Hepatology
Online Access:http://www.sciencedirect.com/science/article/pii/S2352345X17300085