Pharmacokinetics comparison of two pegylated interferon alfa formulations in healthy volunteers

Pharmacokinetics comparison of two pegylated interferon alfa formulations in healthy volunteers

Abstract Background Several countries have used pegylation technology to improve the pharmacokinetic properties of essential drugs. Recently, a novel interferon alfa-2b protein conjugated to four-branched 12 kDa polyethylene glycol molecules was developed jointly between Cuba and Brazil. The aim of...

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Bibliographic Details
Main Authors: Marisa Boff Costa, Paulo Dornelles Picon, Guilherme Becker Sander, Hugo Nodarse Cuni, Carmen Valenzuela Silva, Rolando Páez Meireles, Ana Carolina Magalhães Andrade Góes, Nadia Maria Batoreu, Maria de Lourdes de Sousa Maia, Elizabeth Maciel Albuquerque, Denise Cristina de Souza Matos, Pedro Lopez Saura
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Pharmacology and Toxicology
Subjects:
Pharmacokinetics
Pegylated interferon-alfa
Phase I
Online Access:http://link.springer.com/article/10.1186/s40360-017-0192-z

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http://link.springer.com/article/10.1186/s40360-017-0192-z

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