Centromere binding and a conserved role in chromosome stability for SUMO-dependent ubiquitin ligases.

Centromere binding and a conserved role in chromosome stability for SUMO-dependent ubiquitin ligases.

The Saccharomyces cerevisiae Slx5/8 complex is the founding member of a recently defined class of SUMO-targeted ubiquitin ligases (STUbLs). Slx5/8 has been implicated in genome stability and transcription, but the precise contribution is unclear. To characterise Slx5/8 function, we determined genome...

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Bibliographic Details
Main Authors: Loes A L van de Pasch, Antony J Miles, Wilco Nijenhuis, Nathalie A C H Brabers, Dik van Leenen, Philip Lijnzaad, Markus K Brown, Jimmy Ouellet, Yves Barral, Geert J P L Kops, Frank C P Holstege
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3681975?pdf=render

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http://europepmc.org/articles/PMC3681975?pdf=render

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