An epitope-specific chemically defined nanoparticle vaccine for respiratory syncytial virus

Abstract Respiratory syncytial virus (RSV) can cause severe respiratory disease in humans, particularly in infants and the elderly. However, attempts to develop a safe and effective vaccine have so far been unsuccessful. Atomic-level structures of epitopes targeted by RSV-neutralizing antibodies are...

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Bibliographic Details
Main Authors: Armando Zuniga, Oliver Rassek, Melissa Vrohlings, Aniebrys Marrero-Nodarse, Kerstin Moehle, John A. Robinson, Arin Ghasparian
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-021-00347-y