Efficacy and safety of aflibercept in in vitro and in vivo models of retinoblastoma

Efficacy and safety of aflibercept in in vitro and in vivo models of retinoblastoma

Abstract Background To evaluate the inhibitory effects of aflibercept on the growth and subretinal invasion of retinoblastoma. Methods Xenotransplantation and orthotopic mouse models were created by injecting Y-79 cells subcutaneously and intravitreally, respectively. After induction of retinoblasto...

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Bibliographic Details
Main Authors: Dong Yoon Kim, Jeong A Choi, Jae-Young Koh, Young Hee Yoon
Format: Article
Language:English
Published: BMC 2016-11-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Aflibercept
Retinoblastoma
Choroidal invasion
Treatment
Online Access:http://link.springer.com/article/10.1186/s13046-016-0451-7

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http://link.springer.com/article/10.1186/s13046-016-0451-7

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