Cofactor-mediated conformational control in the bifunctional kinase/RNase Ire1
<p>Abstract</p> <p>Background</p> <p>Ire1 is a signal transduction protein in the endoplasmic reticulum (ER) membrane that serves to adjust the protein-folding capacity of the ER according to the needs of the cell. Ire1 signals, in a transcriptional program, the unfolde...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2011-07-01
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Series: | BMC Biology |
Online Access: | http://www.biomedcentral.com/1741-7007/9/48 |