Cofactor-mediated conformational control in the bifunctional kinase/RNase Ire1

Cofactor-mediated conformational control in the bifunctional kinase/RNase Ire1

<p>Abstract</p> <p>Background</p> <p>Ire1 is a signal transduction protein in the endoplasmic reticulum (ER) membrane that serves to adjust the protein-folding capacity of the ER according to the needs of the cell. Ire1 signals, in a transcriptional program, the unfolde...

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Bibliographic Details
Main Authors: Stroud Robert M, Finer-Moore Janet, Korostelev Andrei A, Egea Pascal F, Korennykh Alexei V, Zhang Chao, Shokat Kevan M, Walter Peter
Format: Article
Language:English
Published: BMC 2011-07-01
Series:BMC Biology
Online Access:http://www.biomedcentral.com/1741-7007/9/48

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http://www.biomedcentral.com/1741-7007/9/48

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