A Bayesian data fusion based approach for learning genome-wide transcriptional regulatory networks
Abstract Background Reverse engineering of transcriptional regulatory networks (TRN) from genomics data has always represented a computational challenge in System Biology. The major issue is modeling the complex crosstalk among transcription factors (TFs) and their target genes, with a method able t...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2020-05-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12859-020-3510-1 |