The Glucose Metabolic Pathway as A Potential Target for Therapeutics: Crucial Role of Glycosylation in Alzheimer’s Disease

The Glucose Metabolic Pathway as A Potential Target for Therapeutics: Crucial Role of Glycosylation in Alzheimer’s Disease

Glucose uptake in the brain decreases because of normal aging but this decline is accelerated in Alzheimer’s disease (AD) patients. In fact, positron emission tomography (PET) studies have shown that metabolic reductions in AD patients occur decades before the onset of symptoms, suggesting that meta...

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Bibliographic Details
Main Authors: Vidyasagar Naik Bukke, Rosanna Villani, Moola Archana, Agata Wawrzyniak, Krzysztof Balawender, Stanislaw Orkisz, Luca Ferraro, Gaetano Serviddio, Tommaso Cassano
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer’s disease
neurodegeneration
post-translational modifications
glycans
glycosylation
phosphorylation
Online Access:https://www.mdpi.com/1422-0067/21/20/7739

Internet

https://www.mdpi.com/1422-0067/21/20/7739

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