Targeted Gene Editing in Human Primary T Cells Using CRISPR/Cas9 Ribonucleoproteins
Background: Clustered regularly interspaced short palindromic repeats/ CRISPR-associated protein 9 (CRISPR/Cas9)-mediated gene knockout of primary T cell has several limitations for clinical applications. Direct delivery of recombinant Cas9 protein and synthetic gRNA, as a pre-assembled ribonucleopr...
| Main Authors: | , , |
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| Format: | Article |
| Language: | fas |
| Published: |
Vesnu Publications
2021-04-01
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| Series: | مجله دانشکده پزشکی اصفهان |
| Subjects: | |
| Online Access: | http://jims.mui.ac.ir/index.php/jims/article/view/13586 |