Design, synthesis, and biological evaluation of novel EF24 and EF31 analogs as potential IκB kinase β inhibitors for the treatment of pancreatic cancer

Design, synthesis, and biological evaluation of novel EF24 and EF31 analogs as potential IκB kinase β inhibitors for the treatment of pancreatic cancer

Xuemeng Xie, Jinfu Tu, Heyi You, Bingren Hu Department of Laparoscopic Surgery, First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China Abstract: Given the important role that inhibitory kappa B (IκB) kinase β (IKK&bet...

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Bibliographic Details
Main Authors: Xie X, Tu J, You H, Hu B
Format: Article
Language:English
Published: Dove Medical Press 2017-05-01
Series:Drug Design, Development and Therapy
Subjects:
Anti-pancreatic cancer activity
IκB kinaseβ
Molecular docking
Molecular dynamics simulation
Online Access:https://www.dovepress.com/design-synthesis-and-biological-evaluation-of-novel-ef24-and-ef31-anal-peer-reviewed-article-DDDT

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https://www.dovepress.com/design-synthesis-and-biological-evaluation-of-novel-ef24-and-ef31-anal-peer-reviewed-article-DDDT

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