Effects of Immunomodulatory Substances on Phagocytosis of A𝛽𝟏-𝟒𝟐 by Human Microglia

Glial activation and increased inflammation characterize neuropathology in Alzheimer's disease (AD). The aim was to develop a model for studying phagocytosis of 𝛽-amyloid (A𝛽) peptide by human microglia and to test effects thereupon by immunomodulatory substances. Human CHME3 microglia showed...

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Bibliographic Details
Main Authors: Erik Hjorth, Dan Frenkel, Howard Weiner, Marianne Schultzberg
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:International Journal of Alzheimer's Disease
Online Access:http://dx.doi.org/10.4061/2010/798424