Intestinal PPARδ protects against diet-induced obesity, insulin resistance and dyslipidemia

Intestinal PPARδ protects against diet-induced obesity, insulin resistance and dyslipidemia

Abstract Peroxisome proliferator-activated receptor δ (PPARδ) is a ligand-activated transcription factor that has an important role in lipid metabolism. Activation of PPARδ stimulates fatty acid oxidation in adipose tissue and skeletal muscle and improves dyslipidemia in mice and humans. PPARδ is hi...

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Bibliographic Details
Main Authors: Marcela Doktorova, Irene Zwarts, Tim van Zutphen, Theo H. van Dijk, Vincent W. Bloks, Liesbeth Harkema, Alain de Bruin, Michael Downes, Ronald M. Evans, Henkjan J. Verkade, Johan W. Jonker
Format: Article
Language:English
Published: Nature Publishing Group 2017-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-00889-z

Internet

https://doi.org/10.1038/s41598-017-00889-z

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