Microfluidic Nano-Scale qPCR Enables Ultra-Sensitive and Quantitative Detection of SARS-CoV-2

Microfluidic Nano-Scale qPCR Enables Ultra-Sensitive and Quantitative Detection of SARS-CoV-2

A major challenge in controlling the COVID-19 pandemic is the high false-negative rate of the commonly used RT-PCR methods for SARS-CoV-2 detection in clinical samples. Accurate detection is particularly challenging in samples with low viral loads that are below the limit of detection (LoD) of stand...

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Bibliographic Details
Main Authors: Xin Xie, Tamara Gjorgjieva, Zaynoun Attieh, Mame Massar Dieng, Marc Arnoux, Mostafa Khair, Yasmine Moussa, Fatima Al Jallaf, Nabil Rahiman, Christopher A. Jackson, Lobna El Messery, Khristine Pamplona, Zyrone Victoria, Mohammed Zafar, Raghib Ali, Fabio Piano, Kristin C. Gunsalus, Youssef Idaghdour
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Processes
Subjects:
SARS-CoV-2
COVID-19
microfluidics
nano-qPCR
ultra-sensitive
viral RNA
Online Access:https://www.mdpi.com/2227-9717/8/11/1425

Internet

https://www.mdpi.com/2227-9717/8/11/1425

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