Decreased autophagy in rat heart induced by anti-β1-adrenergic receptor autoantibodies contributes to the decline in mitochondrial membrane potential.

It has been recognized that changes in mitochondrial structure plays a key role in development of cardiac dysfunction, and autophagy has been shown to exert maintenance of mitochondrial homeostasis effects. Our previous study found that anti-β1-adrenergic receptor autoantibodies (β1-AABs) could lead...

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Bibliographic Details
Main Authors: Li Wang, Keyi Lu, Haihu Hao, Xiaoyu Li, Jie Wang, Ke Wang, Jin Wang, Zi Yan, Suli Zhang, Yunhui Du, Huirong Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24278413/pdf/?tool=EBI