Pre-diagnostic leukocyte genomic DNA methylation and the risk of colorectal cancer in women.

Pre-diagnostic leukocyte genomic DNA methylation and the risk of colorectal cancer in women.

Abnormal one-carbon metabolism may lead to general genomic (global) hypomethylation, which may predispose an individual to the development of colorectal neoplasia.We evaluated the association between pre-diagnostic leukocyte genomic DNA methylation level and the risk of colorectal cancer in a nested...

Full description

Bibliographic Details
Main Authors: Hongmei Nan, Edward L Giovannucci, Kana Wu, Jacob Selhub, Ligi Paul, Bernard Rosner, Charles S Fuchs, Eunyoung Cho
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3613344?pdf=render

Internet

http://europepmc.org/articles/PMC3613344?pdf=render

Similar Items