Platelet-activating factor mediates trinitrobenzene induced dysmotility in the left colon

We investigated whether TNB alters colonic tissue levels of PAF at the expense of changes in colonic motility in the isolated perfused rabbit left colon. Colonic inflammation was induced by the intracolonic administration of 0.25 ml of 50% ethanol containing 30 mg of trinitrobenzene. Strain gauge tr...

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Bibliographic Details
Main Authors: W. E. Longo, J. Standeven, B. Chandel, Y. Deshpande, A. M. Vernava, D. Kaminski
Format: Article
Language:English
Published: Hindawi Limited 1995-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/S0962935195000032