Development and evaluation of a droplet digital PCR assay for the diagnosis of paucibacillary leprosy in skin biopsy specimens.

Development and evaluation of a droplet digital PCR assay for the diagnosis of paucibacillary leprosy in skin biopsy specimens.

BACKGROUND:The reduced amounts of Mycobacterium leprae (M. leprae) among paucibacillary (PB) patients reflect the need to further optimize methods for leprosy diagnosis. An increasing number of reports have shown that droplet digital polymerase chain reaction (ddPCR) is a promising tool for diagnosi...

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Bibliographic Details
Main Authors: Xiujun Cheng, Lele Sun, Qing Zhao, Zihao Mi, Gongqi Yu, Zhenzhen Wang, Yonghu Sun, Chuan Wang, Chunhua Man, Fanghui Fu, Hong Liu, Furen Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-03-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC6438576?pdf=render

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http://europepmc.org/articles/PMC6438576?pdf=render

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