Beneficial Effect of Antibiotics and Microbial Metabolites on Expanded Vδ2Vγ9 T Cells in Hepatocellular Carcinoma Immunotherapy

Beneficial Effect of Antibiotics and Microbial Metabolites on Expanded Vδ2Vγ9 T Cells in Hepatocellular Carcinoma Immunotherapy

Animal experiments and clinical trials have shown that the gut microbiota modulates host immunity and immune checkpoint-mediated responses to tumor cells. However, it remains unclear whether microbiota can also play a role in the tumor immune response of γδT cells, a kind of cell that targets cancer...

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Bibliographic Details
Main Authors: Jiajia Han, Siya Zhang, Yi Xu, Yongsheng Pang, Xue Zhang, Yu Hu, Hui Chen, Wanjun Chen, Jianmin Zhang, Wei He
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-07-01
Series:Frontiers in Immunology
Subjects:
γδT cells
tumor immunotherapy
antibiotics
3-indolepropionic acid
microbiota
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01380/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.01380/full

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