Subgingival microbial communities in Leukocyte Adhesion Deficiency and their relationship with local immunopathology.

Subgingival microbial communities in Leukocyte Adhesion Deficiency and their relationship with local immunopathology.

Leukocyte Adhesion Deficiency I (LAD-I) is a primary immunodeficiency caused by single gene mutations in the CD18 subunit of β2 integrins which result in defective transmigration of neutrophils into the tissues. Affected patients suffer from recurrent life threatening infections and severe oral dise...

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Bibliographic Details
Main Authors: Niki M Moutsopoulos, Natalia I Chalmers, Jennifer J Barb, Loreto Abusleme, Teresa Greenwell-Wild, Nicolas Dutzan, Bruce J Paster, Peter J Munson, Daniel H Fine, Gulbu Uzel, Steven M Holland
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4351202?pdf=render

Internet

http://europepmc.org/articles/PMC4351202?pdf=render

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