Endothelial Dysfunction Accelerates Impairment of Mitochondrial Function in Ageing Kidneys via Inflammasome Activation

Endothelial Dysfunction Accelerates Impairment of Mitochondrial Function in Ageing Kidneys via Inflammasome Activation

Chronic kidney disease is a common problem in the elderly and is associated with increased mortality. We have reported on the role of nitric oxide, which is generated from endothelial nitric oxide synthase (eNOS), in the progression of aged kidneys. To elucidate the role of endothelial dysfunction a...

Full description

Bibliographic Details
Main Authors: Yoshihisa Wada, Reina Umeno, Hajime Nagasu, Megumi Kondo, Atsuyuki Tokuyama, Hiroyuki Kadoya, Kengo Kidokoro, Shun’ichiro Taniguchi, Masafumi Takahashi, Tamaki Sasaki, Naoki Kashihara
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
inflammasome
senescence-associated secretory phenotype
macrophages
mitochondria dysfunction
ASC-deficient mice
Online Access:https://www.mdpi.com/1422-0067/22/17/9269

Internet

https://www.mdpi.com/1422-0067/22/17/9269

Similar Items