Incidence of active pulmonary tuberculosis in patients with coincident filarial and/or intestinal helminth infections followed longitudinally in South India.

Filarial (and other helminth) infections are known to modulate mycobacteria-specific pro-inflammatory cytokine responses necessary for maintaining latency in tuberculosis (TB). We sought to address whether helminth co-infection alters progression to active pulmonary TB in a co-endemic area of South...

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Main Authors: Soumya Chatterjee, Chockalingam Kolappan, Rangasamy Subramani, Punnathanathu G Gopi, Vedhachalam Chandrasekaran, Michael P Fay, Subash Babu, Vasanthapuram Kumaraswami, Thomas B Nutman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3984271?pdf=render