Coagulation factor VIII, white matter hyperintensities and cognitive function: Results from the Cardiovascular Health Study.

<h4>Objective</h4>To investigate the relationship between high FVIII clotting activity (FVIII:C), MRI-defined white matter hyperintensities (WMH) and cognitive function over time.<h4>Methods</h4>Data from the population-based Cardiovascular Health Study (n = 5,888, aged ≥65)...

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Bibliographic Details
Main Authors: Jessica L Rohmann, W T Longstreth, Mary Cushman, Annette L Fitzpatrick, Susan R Heckbert, Kenneth Rice, Frits R Rosendaal, Colleen M Sitlani, Bruce M Psaty, Bob Siegerink
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0242062