Comparable Renal Function at 6 Months with Tacrolimus Combined with Fixed-Dose Sirolimus or MMF: Results of a Randomized Multicenter Trial in Renal Transplantation

In a multicenter trial, renal transplant recipients were randomized to tacrolimus with fixed-dose sirolimus (Tac/SRL, N = 318) or tacrolimus with MMF (Tac/MMF, N = 316). Targeted tacrolimus trough levels were lower in the Tac/SRL group after day 14. The primary endpoint was renal function at 6 month...

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Bibliographic Details
Main Authors: Eveline Van Gurp, Jesus Bustamante, Antonio Franco, Lionel Rostaing, Thomas Becker, Eric Rondeau, Zenon Czajkowski, Andrzej Rydzewski, Antonio Alarcon, Petr Bachleda, Jiri Samlik, Dirk Burmeister, Luis Pallardo, Marie-Christine Moal, Boleslaw Rutkowski, Zbigniew Wlodarczyk
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Journal of Transplantation
Online Access:http://dx.doi.org/10.1155/2010/731426