Optimized Expression and Purification of Humbug in Pichia pastoris and Its Monoclonal Antibody Preparation

Background: The humbug gene is a truncated isoform of Aspartyl β-hydroxylase (ASPH) gene that is overexpressed in many human malignancies. In recent years, since humbug has received increasing attention, it is considered as a potential therapeutic molecular target. Therefore, it is necessary for pr...

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Bibliographic Details
Main Authors: Ting HUYAN, Ruihua TANG, Jing LI, Qi LI, Xiaoping XUE, Hui YANG
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2015-12-01
Series:Iranian Journal of Public Health
Online Access:https://ijph.tums.ac.ir/index.php/ijph/article/view/5559