Synthesis and characterization of functionalized dihydropyrimidinones via one-pot isocyanide-based three-component reaction of N-formyl urea and dialkyl ACETYLENEDICARBOXYLATES

The reactive intermediate generated by the addition of alkyl isocyanides to dialkyl acetylenedicarboxylates was trapped by N-formyl urea to produce highly functionalized dihydropyrimidinones in fairly good yields.

Bibliographic Details
Main Authors: A. Naderi, B. Mohtat
Format: Article
Language:English
Published: Chemical Society of Ethiopia 2017-11-01
Series:Bulletin of the Chemical Society of Ethiopia
Subjects:
Online Access:https://www.ajol.info/index.php/bcse/article/view/163115