Synthesis and characterization of functionalized dihydropyrimidinones via one-pot isocyanide-based three-component reaction of N-formyl urea and dialkyl ACETYLENEDICARBOXYLATES

The reactive intermediate generated by the addition of alkyl isocyanides to dialkyl acetylenedicarboxylates was trapped by N-formyl urea to produce highly functionalized dihydropyrimidinones in fairly good yields.

Bibliographic Details
Main Authors: A. Naderi, B. Mohtat
Format: Article
Language:English
Published: Chemical Society of Ethiopia 2017-11-01
Series:Bulletin of the Chemical Society of Ethiopia
Subjects:
Online Access:https://www.ajol.info/index.php/bcse/article/view/163115
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spelling doaj-ade6561ab8da4e298a855822cae2a4012020-11-24T21:06:06ZengChemical Society of EthiopiaBulletin of the Chemical Society of Ethiopia1011-39241726-801X2017-11-01312345350http://dx.doi.org/10.4314/bcse.v31i2.16Synthesis and characterization of functionalized dihydropyrimidinones via one-pot isocyanide-based three-component reaction of N-formyl urea and dialkyl ACETYLENEDICARBOXYLATESA. NaderiB. MohtatThe reactive intermediate generated by the addition of alkyl isocyanides to dialkyl acetylenedicarboxylates was trapped by N-formyl urea to produce highly functionalized dihydropyrimidinones in fairly good yields.https://www.ajol.info/index.php/bcse/article/view/163115Alkyl isocyanidesDialkyl acetylenedicarboxylateN-Formyl ureaThree-component reactionDihydropyrimidinones
collection DOAJ
language English
format Article
sources DOAJ
author A. Naderi
B. Mohtat
spellingShingle A. Naderi
B. Mohtat
Synthesis and characterization of functionalized dihydropyrimidinones via one-pot isocyanide-based three-component reaction of N-formyl urea and dialkyl ACETYLENEDICARBOXYLATES
Bulletin of the Chemical Society of Ethiopia
Alkyl isocyanides
Dialkyl acetylenedicarboxylate
N-Formyl urea
Three-component reaction
Dihydropyrimidinones
author_facet A. Naderi
B. Mohtat
author_sort A. Naderi
title Synthesis and characterization of functionalized dihydropyrimidinones via one-pot isocyanide-based three-component reaction of N-formyl urea and dialkyl ACETYLENEDICARBOXYLATES
title_short Synthesis and characterization of functionalized dihydropyrimidinones via one-pot isocyanide-based three-component reaction of N-formyl urea and dialkyl ACETYLENEDICARBOXYLATES
title_full Synthesis and characterization of functionalized dihydropyrimidinones via one-pot isocyanide-based three-component reaction of N-formyl urea and dialkyl ACETYLENEDICARBOXYLATES
title_fullStr Synthesis and characterization of functionalized dihydropyrimidinones via one-pot isocyanide-based three-component reaction of N-formyl urea and dialkyl ACETYLENEDICARBOXYLATES
title_full_unstemmed Synthesis and characterization of functionalized dihydropyrimidinones via one-pot isocyanide-based three-component reaction of N-formyl urea and dialkyl ACETYLENEDICARBOXYLATES
title_sort synthesis and characterization of functionalized dihydropyrimidinones via one-pot isocyanide-based three-component reaction of n-formyl urea and dialkyl acetylenedicarboxylates
publisher Chemical Society of Ethiopia
series Bulletin of the Chemical Society of Ethiopia
issn 1011-3924
1726-801X
publishDate 2017-11-01
description The reactive intermediate generated by the addition of alkyl isocyanides to dialkyl acetylenedicarboxylates was trapped by N-formyl urea to produce highly functionalized dihydropyrimidinones in fairly good yields.
topic Alkyl isocyanides
Dialkyl acetylenedicarboxylate
N-Formyl urea
Three-component reaction
Dihydropyrimidinones
url https://www.ajol.info/index.php/bcse/article/view/163115
work_keys_str_mv AT anaderi synthesisandcharacterizationoffunctionalizeddihydropyrimidinonesviaonepotisocyanidebasedthreecomponentreactionofnformylureaanddialkylacetylenedicarboxylates
AT bmohtat synthesisandcharacterizationoffunctionalizeddihydropyrimidinonesviaonepotisocyanidebasedthreecomponentreactionofnformylureaanddialkylacetylenedicarboxylates
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