Ascertaining an appropriate diagnostic algorithm using EGFR mutation-specific antibodies to detect EGFR status in non-small-cell lung cancer.

BACKGROUND: Epidermal growth factor receptor (EGFR) mutation status is the most valuable indicator in the screening of non-small-cell lung cancer (NSCLC) patients for tyrosine kinase inhibitor (TKI) therapy. Accurate, rapid and economical methods of detecting EGFR mutations have become important. Th...

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Bibliographic Details
Main Authors: Guiyang Jiang, Chuifeng Fan, Xiupeng Zhang, Qianze Dong, Liang Wang, Yang Liu, Shundong Dai, Lianhe Yang, Yong Zhang, Juanhan Yu, Enhua Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3594188?pdf=render