S-adenosylmethionine metabolism and liver disease

Methionine is an essential amino acid that is metabolized mainly by the liver where it is converted to S-adenosylmethionine (SAMe) by the enzyme methionine adenosyltransferase. Although all mammalian cells synthesize SAMe, the liver is where the bulk of SAMe is generated as it is the organ where abo...

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Bibliographic Details
Main Authors: José M. Mato, M. Luz Martínez-Chantar, Shelly C. Lu
Format: Article
Language:English
Published: Elsevier 2013-03-01
Series:Annals of Hepatology
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1665268119313559