Post-transcriptional regulation of gene expression in bacterial pathogens by toxin-antitoxin systems

Toxin-antitoxin (TA) systems are small genetic elements ubiquitous in prokaryotic genomes that encode toxic proteins targeting various vital cellular functions. Typically, toxin activity is controlled by adjacently encoded protein or RNA antitoxins and unleashed as a consequence of genetic fluctuati...

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Bibliographic Details
Main Authors: Ralph eBertram, Christopher F Schuster
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2014.00006/full