Evaluation of the genomic DNA extracted from formalin-fixed, paraffin-embedded oral samples archived for the past 40-years Avaliação do DNA genômico obtido de biópsias de boca embebidas em parafina e arquivadas por até 40 anos

BACKGROUND: The most common human archival specimens are formalin-fixed, paraffin-embedded tissues (PETs). DNA can be extracted from PETs, but sometimes, it is unsuitable for molecular techniques as slow degradation of DNA occurs with time. OBJECTIVE: The aim of this study was to verify and discuss...

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Bibliographic Details
Main Authors: Tatiana Nayara Libório, Adriana Etges, Adriana da Costa Neves, Ricardo Alves Mesquita, Fábio Daumas Nunes
Format: Article
Language:English
Published: Sociedade Brasileira de Patologia Clínica 2005-12-01
Series:Jornal Brasileiro de Patologia e Medicina Laboratorial
Subjects:
DNA
PCR
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1676-24442005000600006