Retinal Vessel Responses to Flicker Stimulation Are Impaired in Cav2.3-Deficient Mice—An in-vivo Evaluation Using Retinal Vessel Analysis (RVA)

Retinal Vessel Responses to Flicker Stimulation Are Impaired in Cav2.3-Deficient Mice—An in-vivo Evaluation Using Retinal Vessel Analysis (RVA)

Objective: Metabolic demand increases with neuronal activity and adequate energy supply is ensured by neurovascular coupling (NVC). Impairments of NVC have been reported in the context of several diseases and may correlate with disease severity and outcome. Voltage-gated Ca2+-channels (VGCCs) are in...

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Bibliographic Details
Main Authors: Felix Neumaier, Konstantin Kotliar, Roel Hubert Louis Haeren, Yasin Temel, Jan Niklas Lüke, Osama Seyam, Ute Lindauer, Hans Clusmann, Jürgen Hescheler, Gerrit Alexander Schubert, Toni Schneider, Walid Albanna
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Neurology
Subjects:
in vivo retinal vessel analysis
neurovascular coupling
voltage- gated Ca2+ channels
dynamic retinal vessel analysis
Cav2.3-deficient mice
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2021.659890/full

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https://www.frontiersin.org/articles/10.3389/fneur.2021.659890/full

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