Acyl-Coenzyme A: Cholesterol Acyltransferase (ACAT) in Cholesterol Metabolism: From Its Discovery to Clinical Trials and the Genomics Era

The purification and cloning of the acyl-coenzyme A: cholesterol acyltransferase (ACAT) enzymes and the sterol O-acyltransferase (<i>SOAT</i>) genes has opened new areas of interest in cholesterol metabolism given their profound effects on foam cell biology and intestinal lipid absorptio...

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Bibliographic Details
Main Authors: Qimin Hai, Jonathan D. Smith
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Metabolites
Subjects:
Online Access:https://www.mdpi.com/2218-1989/11/8/543