Alterations in Brain Cannabinoid Receptor Levels Are Associated with HIV-Associated Neurocognitive Disorders in the ART Era: Implications for Therapeutic Strategies Targeting the Endocannabinoid System

Alterations in Brain Cannabinoid Receptor Levels Are Associated with HIV-Associated Neurocognitive Disorders in the ART Era: Implications for Therapeutic Strategies Targeting the Endocannabinoid System

HIV-associated neurocognitive disorders (HAND) persist despite the advent of antiretroviral therapy (ART), suggesting underlying systemic and central nervous system (CNS) inflammatory mechanisms. The endogenous cannabinoid receptors 1 and 2 (CB<sub>1</sub> and CB<sub>2</sub>)...

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Bibliographic Details
Main Authors: Mary K. Swinton, Erin E. Sundermann, Lauren Pedersen, Jacques D. Nguyen, David J. Grelotti, Michael A. Taffe, Jennifer E. Iudicello, Jerel Adam Fields
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Viruses
Subjects:
cannabinoid receptor
inflammation
astrocytes
immunohistochemistry
Online Access:https://www.mdpi.com/1999-4915/13/9/1742

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https://www.mdpi.com/1999-4915/13/9/1742

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