Alterations in Brain Cannabinoid Receptor Levels Are Associated with HIV-Associated Neurocognitive Disorders in the ART Era: Implications for Therapeutic Strategies Targeting the Endocannabinoid System
HIV-associated neurocognitive disorders (HAND) persist despite the advent of antiretroviral therapy (ART), suggesting underlying systemic and central nervous system (CNS) inflammatory mechanisms. The endogenous cannabinoid receptors 1 and 2 (CB<sub>1</sub> and CB<sub>2</sub>)...
Main Authors: | Mary K. Swinton, Erin E. Sundermann, Lauren Pedersen, Jacques D. Nguyen, David J. Grelotti, Michael A. Taffe, Jennifer E. Iudicello, Jerel Adam Fields |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-08-01
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Series: | Viruses |
Subjects: | |
Online Access: | https://www.mdpi.com/1999-4915/13/9/1742 |
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