A high-throughput 3' UTR reporter screening identifies microRNA interactomes of cancer genes.

Despite the established contribution of deregulated microRNA (miRNA) function to carcinogenesis, relatively few miRNA-cancer gene interactions have been validated, making it difficult to appreciate the true complexity of miRNA-cancer gene regulatory networks.In this effort, we identify miRNA interac...

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Bibliographic Details
Main Authors: Gert Van Peer, Evelien Mets, Shana Claeys, Ines De Punt, Steve Lefever, Maté Ongenaert, Pieter Rondou, Frank Speleman, Pieter Mestdagh, Jo Vandesompele
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5844555?pdf=render