Increased expression of the androgen receptor with p300 and interleukin-6 coactivators compensate for oligonucleotide suppression of bcl-2: no increased CREB binding protein or interleukin-4 expression
Background: Antisense oligonucleotides (oligos) have been employed against in vivo and in vitro prostate cancer models targeting growth regulatory proteins. While most oligos have targeted growth factors or their receptors, others have been directed against inhibitors of apoptosis and mediators of a...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2013-04-01
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Series: | Therapeutic Advances in Urology |
Online Access: | https://doi.org/10.1177/1756287212466281 |