Biased localization of actin binding proteins by actin filament conformation

The assembly of actin filaments into distinct cytoskeletal structures plays a critical role in cell physiology. Here, the authors use a combination of live cell imaging and in vitro single molecule binding measurements to show that tandem calponin homology domains (CH1–CH2) are sensitive to actin fi...

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Bibliographic Details
Main Authors: Andrew R. Harris, Pamela Jreij, Brian Belardi, Aaron M. Joffe, Andreas R. Bausch, Daniel A. Fletcher
Format: Article
Language:English
Published: Nature Publishing Group 2020-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19768-9