The Inhibition of RANKL-Induced Osteoclastogenesis through the Suppression of p38 Signaling Pathway by Naringenin and Attenuation of Titanium-Particle-Induced Osteolysis

The Inhibition of RANKL-Induced Osteoclastogenesis through the Suppression of p38 Signaling Pathway by Naringenin and Attenuation of Titanium-Particle-Induced Osteolysis

The aim of this study was to assess the effect of naringenin on osteoclastogenesis and titanium particle-induced osteolysis. Osteolysis from wear-induced particles and aseptic loosening are the most frequent late complications of total joint arthroplasty leading to revision of the prosthesis. Osteol...

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Bibliographic Details
Main Authors: Wengang Wang, Chuanlong Wu, Bo Tian, Xuqiang Liu, Zanjing Zhai, Xinhua Qu, Chuan Jiang, Zhengxiao Ouyang, Yuanqing Mao, Tingting Tang, An Qin, Zhenan Zhu
Format: Article
Language:English
Published: MDPI AG 2014-11-01
Series:International Journal of Molecular Sciences
Subjects:
naringenin
osteolysis
osteoclast
p38 signaling
NFATc1
Online Access:http://www.mdpi.com/1422-0067/15/12/21913

Internet

http://www.mdpi.com/1422-0067/15/12/21913

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