Host Immune Response to ZIKV in an Immunocompetent Embryonic Mouse Model of Intravaginal Infection

Host Immune Response to ZIKV in an Immunocompetent Embryonic Mouse Model of Intravaginal Infection

Zika virus (ZIKV) only induces mild symptoms in adults; however, it can cause congenital Zika syndrome (CZS), including microcephaly. Most of the knowledge on ZIKV pathogenesis was gained using immunocompromised mouse models, which do not fully recapitulate human pathology. Moreover, the study of th...

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Bibliographic Details
Main Authors: Svetlana F. Khaiboullina, Priscila Lopes, Toniana G. de Carvalho, Ana Luiza C. V. Real, Danielle G. Souza, Vivian V. Costa, Mauro M. Teixeira, Enrrico Bloise, Subhash C. Verma, Fabiola M. Ribeiro
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Viruses
Subjects:
ZIKV
FVB/NJ mice
intravaginal infection
CCL2
CXCL1 and CXCL10
Online Access:https://www.mdpi.com/1999-4915/11/6/558

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https://www.mdpi.com/1999-4915/11/6/558

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