The Rho GTPase Cdc42 regulates hair cell planar polarity and cellular patterning in the developing cochlea

Hair cells of the organ of Corti (OC) of the cochlea exhibit distinct planar polarity, both at the tissue and cellular level. Planar polarity at tissue level is manifested as uniform orientation of the hair cell stereociliary bundles. Hair cell intrinsic polarity is defined as structural hair bundle...

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Bibliographic Details
Main Authors: Anna Kirjavainen, Maarja Laos, Tommi Anttonen, Ulla Pirvola
Format: Article
Language:English
Published: The Company of Biologists 2015-03-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/4/4/516