In Situ Maturated Early-Stage Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Improve Cardiac Function by Enhancing Segmental Contraction in Infarcted Rats

In Situ Maturated Early-Stage Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes Improve Cardiac Function by Enhancing Segmental Contraction in Infarcted Rats

The scant ability of cardiomyocytes to proliferate makes heart regeneration one of the biggest challenges of science. Current therapies do not contemplate heart re-muscularization. In this scenario, stem cell-based approaches have been proposed to overcome this lack of regeneration. We hypothesize t...

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Bibliographic Details
Main Authors: Diogo Biagi, Evelyn Thais Fantozzi, Julliana Carvalho Campos-Oliveira, Marcus Vinicius Naghetini, Antonio Fernando Ribeiro, Sirlene Rodrigues, Isabella Ogusuku, Rubia Vanderlinde, Michelle Lopes Araújo Christie, Debora Bastos Mello, Antonio Carlos Campos de Carvalho, Marcos Valadares, Estela Cruvinel, Rafael Dariolli
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Journal of Personalized Medicine
Subjects:
stem cell-therapy
human induced pluripotent stem cells
cardiomyocytes
myocardial infarction
heart failure
regeneration
Online Access:https://www.mdpi.com/2075-4426/11/5/374

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https://www.mdpi.com/2075-4426/11/5/374

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